Package: PathwaySpace 1.3.0

Mauro Castro

PathwaySpace: Spatial Projection of Network Signals along Geodesic Paths

For a given graph containing vertices, edges, and a signal associated with the vertices, the 'PathwaySpace' package performs a convolution operation, which involves a weighted combination of neighboring vertices and their associated signals. The package uses a decay function to project these signals, creating geodesic paths on a 2D-image space. 'PathwaySpace' has various applications, such as visualizing network data in a graphical format that highlights the relationships and signal strengths between vertices. By combining graph theory, signal processing, and visualization, 'PathwaySpace' provides a way of representing graph data on a continuous projection space. Based on methods introduced in Tercan et al. (2025) <doi:10.1016/j.xpro.2025.103681> and Ellrott et al. (2025) <doi:10.1016/j.ccell.2024.12.002>.

Authors:Sysbiolab Team [aut], Victor Apolonio [ctb], Jonathan Back [ctb], Lana Querne [ctb], Vinicius Chagas [ctb], Bahar Tercan [ctb], Mauro Castro [cre]

PathwaySpace_1.3.0.tar.gz
PathwaySpace_1.3.0.zip(r-4.7)PathwaySpace_1.3.0.zip(r-4.6)PathwaySpace_1.3.0.zip(r-4.5)
PathwaySpace_1.3.0.tgz(r-4.6-any)PathwaySpace_1.3.0.tgz(r-4.5-any)
PathwaySpace_1.3.0.tar.gz(r-4.7-any)PathwaySpace_1.3.0.tar.gz(r-4.6-any)
PathwaySpace_1.3.0.tgz(r-4.6-emscripten)
manual.pdf |manual.html
card.svg |card.png
PathwaySpace/json (API)
NEWS

# Install 'PathwaySpace' in R:
install.packages('PathwaySpace', repos = c('https://sysbiolab.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/sysbiolab/pathwayspace/issues

Pkgdown/docs site:https://sysbiolab.github.io

Datasets:
  • CGC_20211118 - COSMIC-CGC genes mapped to PathwaySpace images
  • gdist.toy - A pruned and laid out igraph object from Pathway Commons V12
  • gimage - An image matrix
  • hallmarks - A list with Hallmark gene sets
  • PCv12_pruned_igraph - A pruned and laid out igraph object from Pathway Commons V12

On CRAN:

Conda:

bioinformaticsbiological-networksgraph

5.38 score 2 stars 7 scripts 499 downloads 25 exports 50 dependencies

Last updated from:1f2a4eaff2. Checks:9 OK. Indexed: yes.

TargetResultTimeFilesSyslog
linux-devel-x86_64OK173
source / vignettesOK226
linux-release-x86_64OK169
macos-release-arm64OK93
macos-oldrel-arm64OK87
windows-develOK124
windows-releaseOK112
windows-oldrelOK103
wasm-releaseOK125

Exports:buildPathwaySpacecircularProjectionexpDecaygetNearestNodegetPathwaySpacegs_edge_attr<-gs_vertex_attr<-linearDecaypathDistancesplotPathDistancesplotPathwaySpacepolarDecaypolarProjectionpspace.colspspace.palssignalAggregationsignalDecaysilhouetteMappingsummitMappingsummitWatershedvertexDecayvertexDecay<-vertexSignalvertexSignal<-weibullDecay

Dependencies:base64encbeeswarmCairoclicolorspacecpp11dplyrfarvergenericsggbeeswarmggplot2ggrastrggrepelgluegtableigraphisobandjsonlitelabelinglatticelifecyclemagrittrMatrixpatchworkpillarpkgconfigpngpurrrR6raggRANNRColorBrewerRcppRGraphSpacerlangS7scalesstringistringrsystemfontstextshapingtibbletidygraphtidyrtidyselectutf8vctrsviporviridisLitewithr

Getting started with PathwaySpace projection methods

Rendered fromPathwaySpace.Rmdusingknitr::rmarkdownon May 24 2026.

Last update: 2026-05-18
Started: 2023-09-29

Readme and manuals

Help Manual

Help pageTopics
Constructor of PathwaySpace-class ObjectsbuildPathwaySpace
COSMIC-CGC genes mapped to PathwaySpace imagesCGC_20211118
Circular Projection of Graph-Associated SignalscircularProjection circularProjection,PathwaySpace-method
Constructor of exponential decay functionsexpDecay
getNearestNodegetNearestNode
Accessors for Fetching Slots from a PathwaySpace ObjectgetPathwaySpace getPathwaySpace,PathwaySpace-method
An image matrixgimage
Accessor Functions for PathwaySpace Objectsgs_edge_attr<- gs_edge_attr<-,PathwaySpace-method gs_vertex_attr<- gs_vertex_attr<-,PathwaySpace-method
A list with Hallmark gene sets (v2023.1)hallmarks Hallmarks_v2023_1_Hs_symbols
Constructor of linear decay functionslinearDecay
Calculate a pathway space distance between two vectorspathDistances
PathwaySpace: An S4 class for signal propagation on image spacesPathwaySpace-class
A pruned and laid out igraph object from Pathway Commons V12gdist.toy PCv12_pruned_igraph
Accessory function to plot pathway space distancesplotPathDistances
Plotting 2D-landscape images for the PathwaySpace packageplotPathwaySpace plotPathwaySpace,PathwaySpace-method
Polar transformation functionspolarDecay
Polar Projection of Graph-Associated SignalspolarProjection polarProjection,PathwaySpace-method
A simple vector of colors for PathwaySpace imagespspace.cols
Create interpolated color palettes for PathwaySpace imagespspace.pals
Signal aggregation functionssignalAggregation
Deprecated functionsignalDecay
Decorating PathwaySpace Images with Graph SilhouettessilhouetteMapping silhouetteMapping,PathwaySpace-method
Mapping Summits on PathwaySpace ImagessummitMapping summitMapping,PathwaySpace-method
Variation of the watershed algorithm for summit detectionsummitWatershed
Accessor Functions for PathwaySpace ObjectsvertexDecay vertexDecay,PathwaySpace-method vertexDecay<- vertexDecay<-,PathwaySpace-method vertexSignal vertexSignal,PathwaySpace-method vertexSignal<- vertexSignal<-,PathwaySpace-method
Constructor of Weibull decay functionsweibullDecay